RAK Medical and Health Sciences University is First Medical University in the UAE to Obtain Five Stars in QS Stars Rating     College of Pharmacy at RAK Medical and Health Sciences University has obtained dual national and international accreditation for its Bachelor of Pharmacy program from the American Council for Pharmacy Education (ACPE) and the Commission for Academic Accreditation (CAA)     All Programs are accredited by Ministry of Education, UAE.    All our programs are recognized by the Kingdom of Saudi Arabia.

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Dr. Ikramy Abdelraheem Khalil Ibraheem Profile Picture

Dr. Ikramy Abdelraheem Khalil Ibraheem

Professor

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Education Qualifications
  • Doctor of Philosophy (Pharmaceutical Sciences). Molecular Design of Pharmaceutics – Drug and Gene Delivery. Graduate School of Pharmaceutical Sciences - Hokkaido University – Japan. March, 2006.
  • Master of Pharmaceutical Sciences. Molecular Design of Pharmaceutics – Drug and Gene Delivery. Graduate School of Pharmaceutical Sciences - Hokkaido University – Japan. March, 2003.
  • Bachelor of Pharmaceutical Sciences. Faculty of Pharmacy – Assiut University - Assiut – Egypt. June, 1997.
Experience
  • Professor of Pharmaceutics. RAK Medical and Health Sciences University (Mar 2024~).
  • Professor of Pharmaceutics. Assiut University, Egypt (Jul 2020~).
  • Assistant Professor. Hokkaido University, Hokkaido, Japan (Sep 2016 to Oct 2019).
  • Assistant/Associate Professor. Taibah University, KSA (Oct 2012 to Aug 2016).
  • Associate Professor of Pharmaceutics. Assiut University, Egypt (May 2014 to Jun 2020).
  • Lecturer of Pharmaceutics. Assiut University, Egypt (Jun 2006 to Apr 2014).
Courses Taught
  • Pharmaceutics 2
  • Pharmaceutics 4
  • Pharmaceutical marketing and management
  • Biopharmaceutics and Pharmacokinetics
  • Pharmaceutical Biotechnology
Publications
(since 2018)
  1. M S Ahmed, I A Khalil, K Hassanein, G A El-Gendy, S Ismail. Celecoxib niosomal in-situ gel as a valuable drug delivery system for ocular inflammation. Bulletin of Pharmaceutical Sciences Assiut University, 2023, 46 (2), 757-783.
  2. R Shimosakai, I A Khalil, S Kimura, H Harashima. mRNA-loaded lipid nanoparticles targeting immune cells in the spleen for use as cancer vaccines. Pharmaceuticals. MDPI. 2022, 15(8), 1017-.
  3. M A Younis, Ikramy A Khalil, Yaser HA Elewa, Yasuhiro Kon, Hideyoshi Harashima. Ultra-small lipid nanoparticles encapsulating sorafenib and midkine-siRNA selectively-eradicate sorafenib-resistant hepatocellular carcinoma in vivo. Journal of Controlled Release. 2021, 331, 335-349.
  4. R Hiradate, I A Khalil, A Matsuda, M Sasaki, K Hida, H Harashima. A novel dual-targeted rosiglitazone-loaded nanoparticle for the prevention of diet-induced obesity via the browning of white adipose tissue. Journal of Controlled Release. 2021, 329, 665-675.
  5. S Kimura, I A Khalil, Y HA Elewa, H Harashima. Novel lipid combination for delivery of plasmid DNA to immune cells in the spleen. Journal of Controlled Release. 2021, 330, 753-764.
  6. Y Hagino, I A. Khalil, S Kimura, K Kusumoto, and H Harashima. GALA-Modified Lipid Nanoparticles for the Targeted Delivery of Plasmid DNA to the Lungs. Mol. Pharmaceutics 2021, 18, 3, 878–888.
  7. Younis MA, Khalil IA, Harashima H: Gene Therapy for Hepatocellular Carcinoma; Highlighting the Journey from Theory to Clinical Applications. Advanced Therapeutics, 3.11(2020) 2000087.
  8. Khalil IA, Harashima H: The GALA peptide: Multiple roles in drug and gene delivery. Bulletin of Pharmaceutical Sciences. Assiut (2020) (accepted manuscript).
  9. Khalil IA, Younis MA, Kimura S, Harashima H: Lipid nanoparticles for cell-specific in vivo targeted delivery of nucleic acids. Biol Pharm Bull (2019) (accepted manuscript).
  10. Kimura S, Khalil IA (Corresponding author), Elewa YHA, Harashima H: Spleen selective enhancement of transfection activities of plasmid DNA driven by octaarginine and an ionizable lipid and its implications for cancer immunization. Journal of controlled release (2019) 313: 70-79.
  11. Khalil IA, Sato Y, Harashima H: Recent advances in the targeting of systemically administered non-viral gene delivery systems. Expert opinion on drug delivery (2019) 16: 1037-1050.
  12. Younis MA, Khalil IA, Abd Elwakil MM, Harashima H: A Multifunctional Lipid-based Nanodevice for the Highly-specific Co-delivery of Sorafenib and Midkine siRNA to Hepatic Cancer Cells. Mol. Pharmaceutics (2019), 16: 4031-4044.
  13. Nakamura T, Yamada Y, Sato Y, Khalil IA, Harashima H: Innovative nanotechnologies for enhancing nucleic acids/gene therapy: Controlling intracellular trafficking to targeted biodistribution. Biomaterials (2019) 119329.
  14. Santiwarangkool S, Akita H, Khalil IA, Abd Elwakil MM, Sato Y, Kusumoto K, Harashima H: A study of the endocytosis mechanism and transendothelial activity of lung-targeted GALA-modified liposomes. J Control Release (2019) 307:55-63.
  15. Abd Elwakil MM, Khalil IA, Elewa YHA, Kusumoto K, Sato Y, Shobaki N, Kon Y, Harashima H: Lung-endothelium-targeted nanoparticles based on a ph-sensitive lipid and the gala peptide enable robust gene silencing and the regression of metastatic lung cancer. Advanced Functional Materials (2019) 29(18):1807677.
  16. Khalil IA, Yamada Y, Harashima H: Optimization of siRNA delivery to target sites: Issues and future directions. Expert Opin Drug Deliv (2018) 1-13.
  17. Khalil IA, Kimura S, Sato Y, Harashima H: Synergism between a cell penetrating peptide and a ph-sensitive cationic lipid in efficient gene delivery based on double-coated nanoparticles. J Control Release (2018) 275:107-116.
  18. Khalil IA, Harashima H: An efficient pegylated gene delivery system with improved targeting: Synergism between octaarginine and a fusogenic peptide. Int J Pharm (2018) 538(1-2):179-187.
Achievements
  • Award from the Arab Company for Drug Industries and Medical Appliances (ACDIMA) for the best publication (July 2020). 
  • A post-doctor research fellow from Japan Society for the Promotion of Science (JSPS) (Sep 2007 to Sep 2009).
  • Nagai Konishi Student Award – From Nagai Foundation – Tokyo – Japan (Sep 2005).
  • Best poster for young researchers (2nd) – From the 9th Liposome Research Days (LRD) 2004 – Taiwan (May 2004).